Biosynthesis of the metallic nanoparticle is gaining importance because it’s a single-step process, nontoxic, environmentally acceptable, and easily scaled up. The present study investigated the biosynthesis of silver nanoparticles (AgNPs) via reacting olive wastewater filtrate (OWF) with silver nitrate, and the formation of AgNPs was confirmed by a color change of the reaction mixture and visible spectrophotometry. Additionally, the influence of pH, reaction time, AgNO₃ concentration, temperature, and OWF volume on the proposed method was investigated. It was found that with increasing the previously mentioned parameters, the formation of the AgNPs was increased under the experimental conditions. The results showed that OWF represented a promising material for the biosynthesis of AgNPs.      

A convenient method of preparing ultrafine polystyrene latex nano-particles with chlorine groups on the surface is developed. Polystyrene latexes in the size range 50–400 nm were prepared via emulsion polymerization, using sodium dodecyl sulfate (SDS) as surfactant. The poly styrene with chlorine groups on the surface will be fine to use as organic filler to modify rubber. Transmission electron microscopy (TEM) was used to observe the morphology of silicon dioxide and functionalized polystyrene nanoparticles. The nature of bonding between the polymer and the reactive groups on the filler surfaces was analyzed using Fourier transform infrared spectroscopy (FTIR). Scanning electron microscopy (SEM) was employed to examine the filler surface.

ABSTRACT

Natural polymers with improved structure have been securing increasing value in the industry as they

are abundant, cheap, and biodegradable. Graft copolymerization is one of the effective ways to

enhance the properties of natural polymers. Starch based graft copolymers are becoming increasingly

important due to their remarkable adhesion, high water absorbency, and biodegradability. Methyl

methacrylate (MMA) grafted onto starch by using the ceric ammonium nitrate (CAN) as a redox

initiator in the presence of nitric acid in aqueous medium to form grafted copolymer (Starch-g-

PMMA) was investigated. The grafting reaction was carried out under stream of nitrogen gas. The

impact of different reaction parameters to achieve the highest percent grafting (%G) has been studied

by determining the initiator concentration, monomer concentration, time (hours), nitric acid

concentration, and polymerization temperature. The % G was found to be 97%. Evidence of grafting

was characterized and confirmed by Fourier transform infrared spectroscopy (FTIR). The peaks at

1736.70 cm-1 and 3449.78 cm-1 indicates that MMA has been successfully grafted to starch. %G was

found to be decreased at higher than 70°C, after 2 hours of reaction time, with an increase of MMA

monomer concentration, initiator concentration, and with HNO3 concentration. The highest percent

grafting was obtained at the parameters of 1 g starch, 70°C, 2 hours, 2 mmol CAN, 140 mmol MMA

and 0.4 mmol HNO3

ABSTRACT Chronic rheumatoid arthritis (RA) is a systemic inflammatory disease that leads to cartilage and bone erosion. Untreated disease is linked with joint deformity and substantial health care related costs. Conventional disease-modifying anti-rheumatic drugs (DMARDs) are the main tool to treat any form of RA. Methotrexate (MTX) is the key conventional DMARDs. It is recommended as a first-line treatment for patients with RA. However, MTX is potentially associated with various toxicities. No clear pattern of MTX use in patients with RA in Libya, since no national guideline has been implanted so far. The aim was to investigate the prescribing patterns of MTX in Libya. A hundred and twenty patients who were on treatment with MTX and follow up in RA clinic of Tripoli University hospital were evaluated for therapy during the period of 2018 and 2019. Patient distribution data, disease duration, other related diseases and drug prescribed as well as adverse drug reactions were considered to analyze the pattern of drug use. The demographic distribution findings indicate that female patients are more than male patients and the ratio of disease among female to male was 1:9. A range of age between 41 - 60 years was the highest affected compared with other ages. Among of these about 75% of patients were no occupational works. RA related diseases were found to be more with diabetes mellitus, hypertension and osteoporosis. Low use of NSAIDs in this group of patients but with high use of steroid. A high group of patient's use of low dose of MTX for up to five years. This study concludes that MTX is an effective drug in controlling the disease with less and tolerated incidence of side effects. 

Abstract: Sitagliptin is a drug used in treatment of type 2 diabetes mellitus. Incretin hormones, including glucagonlike peptide-1 analogue and dipeptidyl peptidase-4 inhibitor have recently been found to regulate glucose metabolism. Thus, the aim of this study was to evaluate the effect of sitagliptin on glycemic control and it is associated side effects in Libyan patients with type 2 diabetes, who had inadequate response to existing anti-diabetic drugs. Hundred patients with a known history of type 2 diabetes were recruited in this study during the period of 2019 and 2020. Sitagliptin (100 mg daily) was added on to the pre-existing therapy for type 2 diabetes and the main outcome measures were a change from the base line in glycated hemoglobin and fasting plasma sugar as well as the incidence of symptomatic hypoglycemia. All patients were engaged from outpatient clinic of National Diabetes and Endocrinology Center at Tripoli, Libya. The findings show that the actions of dipeptidyl peptidase-4 inhibitors improve glycaemic control in the patients, and glycated hemoglobin as well as fasting plasma sugar. Thus, sitagliptin is a profound drug for a comprehensive treatment of patients with type 2 diabetes with a low incidence of hypoglycemia.