Solventless melt electrospinning which allows mass production is substantially safe. It can produce fibres of hundreds of nanometres, one order of magnitude lower than that of conventional melt-blown spinning. In this paper, a comparison between different technologies producing ultra-fine fibre reveals the advancement of melt electrospinning method using umbellate spinneret for ultra-fine fibre mass production. Some typical industrial polymer materials was also spun using melt electrospinng method, including biodegradable materials like polylactic acid and polycaprolactone (PCL), which may contribute to some interesting applications. In addition, a machine for mass production is also proposed. Finally, proposition of the industrialisation of ultra-fine fibre by melt electrospinning is discussed.

Libya as many other regions under arid climates suffers from inadequate water resources to cover all the needs of this rapidly developing country. Increasing water amounts for population supply, agricultural irrigation and use for industry are needed. As groundwater is the main water source in the country it represents a natural resource of the highest economic and social importance. FEFLOW numerical model was implemented in a regional scale to show how the natural situation has been changed after heavy groundwater abstraction having occurred in the last decades in the northwestern part of Libya. Results of the numerical model indicated that the current zones of depression in piezometric surface could have been caused by smaller withdrawn amounts than previously estimated. Indicated differences in assessed withdrawn groundwater volumes seem to be quite high and might influence considerably the future possibilities of groundwater use in the study.

Keywords

Jifarah plain, groundwater, Coastal aquifer, Stalinization, FEFLOW model

The paper examines the factors that may be considered as challenges or difficulties facing the implementation of the international accounting standards (IASs) and international financial reporting standards (IFRSs) by Libyan companies listed on the Libyan Stock Market (LSM).

Circulating microvesicles (cMVs) are the extracellular MVs released from the cells in the blood and on the vascular wall. Our previous study demonstrates that cMVs of diabetic mouse are detrimental to endothelial progenitor cells (EPCs), which are known to be very important for maintaining normal endothelial function and structure. In this study, we compared the levels of circulating EPCs and EPC-derived MVs (EPC-MVs) in diabetic and healthy subjects. Also, the migration ability, apoptosis rate and reactive oxygen species (ROS) production of EPCs cultured from diabetic and healthy subjects were determined. More importantly, we evaluated whether cMVs from healthy subjects (ch-MVs) improves the function of EPCs from diabetic patients (d-EPCs), and whether cMVs from diabetic patients (cd-MVs) impairs the function of EPCs from healthy subjects (h-EPCs). The d-EPCs or h-EPCs were incubated with ch-MVs or cd-MVs for 24 hours. The migration ability of EPCs was analyzed by an assay kit. The apoptotic rate and ROS production were analyzed by labeling with propidium iodide (PI) and dihydroethidium (DHE) respectively, followed with flow cytometeric analysis. Our data showed that (1) there was a decrease in EPCs iv and an elevation in EPC-MVs in diabetic patients when compared to healthy subjects; (2) The migration ability of d-EPCs were decreased, and the apoptosis rate and ROS production were increased in d-EPCs; (3) ch-MVs improve the function of d-EPC through improving its migration ability and decreasing the apoptosis and ROS production; (4) cd-MVs increase h-EPC apoptosis, and increase ROS production. We conclude that cMVs modulate EPC function and this role of cMVs is reversed in diabetes with the mechanism linked to ROS production.